000 02233cam a22002537a 4500
001 u23593
003 KWAREICT
005 20210719100623.0
008 130311s2013 enka b 001 0 eng d
020 _a9780123878298
020 _a0123878292
035 _a(Kwareict) u23593
040 _cKwareTech
082 0 0 _a616.7/1042
_223
245 0 0 _aGenetics of bone biology and skeletal disease /
_cedited by Rajesh V. Thakker ... [et al.].
260 _aLondon ;
_aWaltham, MA :
_bAcademic Press,
_c2013.
300 _axi, 621 p., [14] p. of col. plates :
_bill. (some col.) ;
_c29 cm.
504 _aIncludes bibliographical references and index.
520 _aThis book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general introductory chapters on genetics and bone biology and more specific disease-orientated chapters, which comprehensively summarize the clinical, genetic, molecular genetic, animal model, functional and molecular pathology, diagnostic, counselling and treatment aspects of each disorder. Saves academic, medical, and pharma researchers time in quickly accessing the very latest details on a broad range of genetic bone issues, as opposed to searching through thousands of journal articles. Provides a common language for bone biologists and geneticists to discuss the development of bone cells and genetics and their interactions in the development of disease Researchers in all areas bone biology and genetics will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays. For those clinical researchers who are also MDs, correct diagnosis (and therefore correct treatment) of bone diseases depends on a strong understanding of the molecular basis for the disease--
_cSource other than Library of Congress.
650 0 _aBones
_xDiseases
_xGenetic aspects.
650 1 2 _aBone Diseases
_xgenetics.
700 1 _aThakker, R. V.
942 _2ddc
_cBOOK
999 _c680
_d680